Expresión de búsqueda: RECEPTOR TYROSINE KINASE-LIKE ORPHAN RECEPTORS 
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Descriptor Inglés:   Receptor Tyrosine Kinase-like Orphan Receptors 
Descriptor Español:   Receptores Huérfanos Similares al Receptor Tirosina Quinasa 
Descriptor Portugués:   Receptores Órfãos Semelhantes a Receptor Tirosina Quinase 
Categoría:   D08.811.913.696.620.682.725.400.093
D12.776.543.750.060.233
Definición Inglés:   A family of cell surface receptors that were originally identified by their structural homology to neurotropic TYROSINE KINASES and referred to as orphan receptors because the associated ligand and signaling pathways were unknown. Evidence for the functionality of these proteins has been established by experiments showing that disruption of the orphan receptor genes results in developmental defects. 
Nota de Indización Inglés:   do not confuse with ORPHAN NUCLEAR RECEPTORS
Nota Histórica Inglés:   2010 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AG agonists AN analysis
AI antagonists & inhibitors BI biosynthesis
BL blood CF cerebrospinal fluid
CS chemical synthesis CH chemistry
CL classification CT contraindications
DF deficiency DE drug effects
EC economics GE genetics
HI history IM immunology
IP isolation & purification ME metabolism
PK pharmacokinetics PD pharmacology
PH physiology PO poisoning
RE radiation effects SE secretion
ST standards SD supply & distribution
TU therapeutic use TO toxicity
UL ultrastructure UR urine
Número del Registro:   53614 
Identificador Único:   D057050 

Ocurrencia en la BVS:
 

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